New studies show that the use of probiotic supplements in childhood by women with polycystic ovary syndrome or PCOS has many advantages.
This review observed that probiotics/synbiotics were effective in improving hormonal profiles, lipid levels, and inflammation associated with this disease. It shows the potential of probiotics to improve the symptoms of polycystic ovary syndrome.
PCOS may originate in the early stages of development and become more severe later in adolescence; Monitoring the microbiome and early probiotic supplementation in childhood and adolescence can be useful for modulating dysbiosis (an imbalance of microbial species in the body) to prevent and correct PCOS.
PCOS prevalence
Polycystic ovary syndrome is a very common disease among women of reproductive age, affecting up to 15% of the population. If you have clinical or biochemical hyperandrogenism and no ovulation, the probability of having a polycystic ovary increases. It is known that obesity plays an important role in the development of this syndrome.
Research shows that the microbiota has a great impact on the development of polycystic ovary.
After confirming the link between obesity, polycystic ovary syndrome, and dysbiosis, it was found that dysbiosis occurs more in women with PCOS.
The gut microbiome of women with PCOS is characterized by less diversity than that of healthy women.
The decrease in microbial diversity in PCOS is often associated with a decrease in beneficial bacteria such as lactobacilli and bifidobacteria, and also causes an increase in pathogenic bacteria such as Escherichia coli and Shigella.
Therefore, the findings suggest that probiotic supplements containing such bacteria may be beneficial for women with PCOS, but emphasize that more studies are needed to confirm this connection.
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